Polydrug abuse among opioid maintenance treatment patients is related to inadequate dose of maintenance treatment medicine

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Polydrug abuse among opioid maintenance treatment patients is related to inadequate dose of maintenance treatment medicine

BACKGROUND Polydrug abuse is a known problem among opioid-dependent patients receiving opioid maintenance treatment (OMT). However, improved laboratory diagnostics is required to reveal polydrug abuse in its current scope. Furthermore, there are few studies focusing on the relationship between polydrug abuse and adequacy of the dose of OMT medicine. This study aimed to evaluate the polydrug abu...

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Prescription opioid abuse among enrollees into methadone maintenance treatment.

A multi-state survey of 5663 opioid dependent persons enrolling in 72 methadone maintenance treatment programs (MMTPs) was conducted to determine the prevalence of prescription opioid (PO) abuse, factors associated with PO abuse and sources for POs. Regions where PO abuse was believed to be prevalent were oversampled; primary opioid was defined as the drug used the most before coming to the MMT...

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Dose-Dependent Effects of Methadone on QT interval in Patients under Methadone Maintenance Treatment

Background: The role of methadone in QTc prolongation, Torsades de Pointes (TdP) arrhythmia and sudden cardiac death has been debated. Because of widespread use of methadone in methadone maintenance treatment (MMT) centers, we aimed to study dose-related effects of methadone on QTc prolongation. Methods: In a comparative observational study, 90 patients who were under MMT were evaluated. Patien...

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Prescription drug use among pregnant women in opioid Maintenance Treatment.

AIMS This study describes the use of prescribed drugs among women in opioid maintenance treatment (OMT) prior to, and during, pregnancy. DESIGN This cohort study was based on data from two nationwide databases: the Medical Birth Registry of Norway and the Norwegian Prescription Database. SETTING Norway, 2004-2010. PARTICIPANTS OMT drugs were dispensed to 138 women with 159 pregnancies. ...

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Social and structural barriers for adherence to methadone maintenance treatment among Vietnamese opioid dependence patients

INTRODUCTION Methadone maintenance treatment (MMT) services may reduce the risk of HIV transmission if patients completely adhere to the treatment. Identifying adherence patterns and potential related factors is vital for the sustainability of MMT program in Vietnam. This study examined social and structural factors associated with adherence to MMT among patients in different service delivery m...

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ژورنال

عنوان ژورنال: BMC Psychiatry

سال: 2017

ISSN: 1471-244X

DOI: 10.1186/s12888-017-1415-y